韩桂茹在插队时与安国庆相恋，后被其无情抛弃，从而跳河自杀。命是救回来了，但是终身不能再生育。四十年后，韩桂茹在户外排练时中暑，被闺蜜吴英送至附近的“夕阳红乐园”休息。二人发现“夕阳红乐园”的老板正是安国庆。如今的安国庆虽然实现了年轻时的理想抱负，却尝尽了“众叛亲离”的滋味。安国庆现在的心愿有三，一是弥补韩桂茹的痛苦，二是求得老友许慕的原谅，三是找到自己失散的女儿。
They Might be Giants chronicles the adventures of Sherlock Holmes and Dr. Watson in modern-day New York City. The fact that Sherlock Holmes is a psychotic paranoid and Dr. Watson is a female psychiatrist fascinated by his case is almost beside the point. Dr. Watson follows Holmes across Manhattan and is, against her better judgment, drawn into the master detective's world of intrigue and danger. This is a sweet, goofy and fairly romantic film that asks the questions Whose reality is right...and does it really matter
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